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Doctors Best

Doctors Best SAMe 400mg Double-Strength 60 Tablet

Doctors Best

Doctors Best SAMe 400mg Double-Strength 60 Tablet

Barcode: 753950002524
Size: 60
Form: Tablet

10% off when ordering multiple items

SAMe 400mg Double-Strength

Product Description

Doctor's Best utilizes only the highest quality Italian Soloesse SAM-e providing slow and targeted release for improved GI tolerance and absorption. Our Double-Strength SAM-e 400 contains 400 mg of active Soloesse SAM-e in each tablet. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.

Doctor's Best SAM-e helps replenish your SAM-e levels and promote a healthy mood. SAM-e S-Adenosyl-L-Methionine is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody.

Supplementing with SAM-e

Soloesse Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate bio-chemical activity in the human body.

SAM-e and Mood and Cognitive Function

SAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.

SAM-e and Joint Function

In clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.

SAM-e and Liver Function

SAM-e helps support healthy levels of glutathione, a critical anti-oxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.

Double Strength SAM-e is sealed in blister packs for freshness and stability.

  • Doctors Best SAM-e is proven to enhance mood and promote cognitive health*
  • SAM-e is essential for the healthy metabolism of the major brain transmitters dopamine, serotonin and norepinephrine*
  • SAM-e has been proven to promote joint comfort and mobility and supports liver health and detoxification*
  • Pharmaceutical grade materials
  • Gluten Free/Soy Free/Vegan

Suggested Usage Take 1 tablet daily between meals, or as directed by a nutritionally-informed physician. Do not chew or crush tablet.


Supplement Facts

Serving Size 1 Tablet Servings Per Container 60

Amount Per Serving % Daily Value***

SAM-e S-Adenosyl Methionine disulfate p-toluensulfonate 400 mg *


*Daily Value Not Established
***Percent Daily Values are based on a 2,000 calorie diet

Other IngredientsMictoctystalline cellulose,stearic acid,calcium chloride anhydrous,magnesium silicate,magnesium silicate,magnesium hydroxide,flake shellac dewaxed,glycerol,silica,arginine base,sodium alginate,calcium oxide.


WarningsKeep out of reach of children. As with all dietary supplements, consult your healthcare professional before use. See product label for more information. Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAM-e. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.


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