FREE SHIPPING on all orders to continental US!

Douglas Laboratories

Douglas Laboratories Zinc Picolinate 20mg 100 Tablets

Douglas Laboratories

Douglas Laboratories Zinc Picolinate 20mg 100 Tablets

Barcode: 745287030554
Size: 100
Form: Tablet

Zinc Picolinate

Dietary Zinc Supplement

DESCRIPTION

Zinc Picolinate tablets, provided by Douglas Laboratories, supply bioavailable zinc bound to picolinic acid. Each tablet contains 20 mg zinc, exclusively in the form of zinc picolinate.

FUNCTIONS

Zinc is an essential trace element involved in most major metabolic pathways. General signs of human zinc deficiency indicate that zinc has important functions in maintaining immune function, reproduction, healthy skin, and growth.

Numerous studies support the fundamental role of zinc in normal immune response in humans. Immune cells must be able to rapidly divide in order to respond to daily challenges. Like all rapidly dividing cells, immune cells depend on adequate amounts of dietary zinc.

As a cofactor of the antioxidant enzyme superoxide dismutase SOD , zinc can be considered an antioxidant nutrient. Zinc supplementation has been shown to increase the antioxidant activity of SOD, and provide increased free radical protection. Zinc deficiency is associated with increased oxidative damage.

Absorption of toxic heavy metals, especially cadmium and lead, is lower in individuals with high zinc status compared to those with low zinc status. The body pool of readily available zinc appears to be small, which renders the body susceptible to deficiency and therefore dependent on a steady dietary supply of bioavailable zinc. While typical zinc intakes in U.S. adults are between 10 and 15 mg per day, which approach the RDA, intakes in the elderly are often low. Pregnant women are also at risk for zinc deficiency, since they have a higher requirement for this trace element. Frequently, vegetarians and chronically depressed individuals have been found to have low zinc status.

Human and animal studies show that zinc picolinate is well absorbed and retained compared to many other zinc supplements tested. Picolinic acid is an isomer of nicotinic acid niacin and a natural metabolite of tryptophan. It acts as a potent chelator of metals in nature.

INDICATIONS

Zinc Picolinate may be a useful nutritional adjunct for individuals who wish to increase their intake of zinc.

FORMULA ZNP

Each tablet contains

Zinc picolinate ............................................20 mg

SUGGESTED USE

One tablet daily as a dietary supplement, or as directed by a physician.

SIDE EFFECTS

No adverse effects have been reported.

STORAGE

Store in a cool, dry place, away from direct light.

Keep out of reach of children.

REFERENCES

Abdallah SM, Samman S. The effect of increasing dietary zinc on the activity of superoxide dismutase and zinc concentration in erythrocytes of healthy female subjects. Eur J Clin Nutr 1993;47 327-332.

Brignola C, Belloli C, De Simone G, et al. Zinc supplementation restores plasma concentrations of zinc and thymulin in patients with Crohn's disease. Aliment Pharmacol Ther 1993;7 275-280.

Food and Nutrition Board, National Research Council. Recommended Dietary Allowances. 10th ed. Washington, D.C. National Academy Press, 1989.

Donovan UM, Gibson RS. Iron and zinc status of young women aged 14 to 19 years consuming vegetarian and omnivorous diets. J Am Coll Nutr 1995;14 463-472.

Goyer RA. Nutrition and metal toxicity. Am J Clin Nutr 1995;61 Suppl.646S-650S.

Gupta RK, Bhattacharya SK, Sundar S, Kumar K, Kachhawaha JS, Sen PC. A correlative study of serum zinc and in vivo cell mediated immune status in rheumatic heart disease. Acta Cardiol 1996;47 297-304.

Hong Bin Q, Garfinkel D. The cadmium toxicity hypothesis of aging A possible explanation for the zinc deficiency hypothesis of aging. Med Hypotheses 1994;42 380-384.

Keen CL, Gershwin ME. Zinc deficiency and immune function. Annu Rev Nutr 1990;10 415-431.

King JC, Keen CL. Zinc. In Shils ME, Olson JA, Shike M, eds. Modern Nutrition in Health and Disease. 8th ed. Philadelphia Lea & Febiger, 1994 214-230.

Maes M, D'Haese PC, Scharp S, D'Hondt P, Cosyns P, De Broe ME. Hypozincemia in depression. J Affect Disord 1994;31 135-140.

Mares-Perlman JA, Subar AF, Block G, Greger JL, Luby MH. Zinc intake and sources in the US adult population 1976- 1980. J Am Coll Nutr 1995;14 349-357.

Mei W, Dong ZM, Liao BL, Xu HB. Study of immune function of cancer patients influenced by supplemental zinc or selenium-zinc combination. Biol Trace Elem Res 1991;28 11-19.

Olin KL, Golub MS, Gershwin ME, Hendrickx AG, Lonnerdal B, Keen CL. Extracellular superoxide dismutase activity is affected by dietary zinc intake in nonhuman primate and rodent models. Am J Clin Nutr 1995;61 1263-1267.

Oteiza PI, Olin KL, Fraga CG, Keen CL. Zinc deficiency causes oxidative damage to proteins, lipids and DNA in rat testes. J Nutr 1995;125 823-829.

Prasad AS. Zinc an overview. Nutrition 1995;11 93-99.

Prasad AS, Fitzgerald JT, Hess JW, Kaplan J, Pelen F, Dardenne M. Zinc deficiency in elderly patients. Nutrition 1993;9 218-224.

Roebothan BV, Chandra RK. Nutrient consumption and body size in a group of institutionalized elderly. Nutr Res 1994;14 35-39.

Sherman AR. Zinc, copper, and iron nutriture and immunity. J Nutr 1992;122 604-609.

Singh A, Failla ML, Deuster PA. Exercise-induced changes in immune function Effects of zinc supplementation. J Appl Physiol 1994;76 2298-2303.

Small SP, Best DG, Hustins KA. Energy and nutrient intakes of independently-living, elderly women. Can J Nurs Res 1994;26 71-81.


NOTICE:

International Customers:Unfortunately we are not able to ship Douglas Laboratories products internationally. We sincerely apologize for any inconvenience.



Subscribe